Abstract- Due to technological advancement and population growth, the use of synthetic plastic materials increases day by day,which not only a threat to us, but also the whole biological community. Hence, scientist and researchers are focusing on newpolymer and composite materials, which are compatible with various applications ranging from issues related to electronics,packaging and advanced medical applications used in our day to day life. This review mainly focused on fabrication methods ofbiobased polymer composites and nanocomposites mainly melt-extrusion, electrospinning, solution mixing, in situ methods andlatex technology. Especially, more attention is drawn towards the field of biomedical applications which mainly includes tissueengineering including skin, oral tissues, blood vessels and bone, wound dressing and dental resin-based biocomposites.Keywords: Polymer composites, electrospinning technique, tissue engineering, wound dressing