Diabetes mellitus is achronic metabolic disorder characterized by hyperglycemia caused by defective insulin secretion, resistance to insulin action or combination of both.Frequent administration of antidiabetic drug dosage form leads to some side effects and affect on patients compliance, so there is need to develop asustained release dosage form to enhance patients compliance and reduced dosing frequency. So attempt has been made to prepare and evaluate subdermalbiodegradable implants of Glipizide.
Keywords:-Diabetes, Implants,Glipizide, Alloxan Induced, Antihyperglycemic.